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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-17
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pubmed:abstractText |
Krüppel-like factor 11 (KLF11) is a transcriptional factor of the zinc finger domain family that regulates the expression of insulin. In North European populations, its common functional variant Q62R (rs35927125) is a strong genetic factor for Type 2 diabetes (P = 0.00033, odds ratio for G allele = 1.29, 95% CI 1.12-1.49). We examined the contribution of KLF11 variants to the susceptibility to Type 2 diabetes in a Japanese population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1464-5491
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pubmed:author |
pubmed-author:InoueHH,
pubmed-author:ItakuraMM,
pubmed-author:KeshavarzPP,
pubmed-author:KunikaKK,
pubmed-author:MiyawakiKK,
pubmed-author:MoritaniMM,
pubmed-author:NakamuraNN,
pubmed-author:ShinoharaKK,
pubmed-author:ShiotaHH,
pubmed-author:TanahashiTT,
pubmed-author:YamaguchiYY,
pubmed-author:YoshikawaTT
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-26
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18199129-Adult,
pubmed-meshheading:18199129-Analysis of Variance,
pubmed-meshheading:18199129-Asian Continental Ancestry Group,
pubmed-meshheading:18199129-Cell Cycle Proteins,
pubmed-meshheading:18199129-Diabetes Mellitus, Type 2,
pubmed-meshheading:18199129-Female,
pubmed-meshheading:18199129-Gene Frequency,
pubmed-meshheading:18199129-Genetic Predisposition to Disease,
pubmed-meshheading:18199129-Genotype,
pubmed-meshheading:18199129-Humans,
pubmed-meshheading:18199129-Insulin,
pubmed-meshheading:18199129-Japan,
pubmed-meshheading:18199129-Linkage Disequilibrium,
pubmed-meshheading:18199129-Male,
pubmed-meshheading:18199129-Middle Aged,
pubmed-meshheading:18199129-Repressor Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population.
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pubmed:affiliation |
Division of Genetic Information, Institute for Genome Research, University of Tokushima, Tokushima, Japan. tana@genome.tokushima-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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