Linked Life Data

18198675

Source:http://linkedlifedata.com/resource/pubmed/id/18198675

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2008-1-17
pubmed:abstractText
The peculiarities of structure and cellular composition of the thymus in male Wistar rats were studied using histological, morphometric methods and electron microscopy during the adaptation to physical loads (swimming), which were applied simultaneously with the administration of the immunomodulator diucifon and in the late stages of a rehabilitation period after cessation of the training process. Training performed with the simultaneous correction with diucifon resulted in the changes that were indicative of the increased reserve capacity of the immune system (increase in the relative area of the cortex in thymus sections, augmentation of the number of blast cells, medium lymphocytes and mitotically dividing cells). The degree of these changes was different in animals with various adaptation capacity, which is indicative of the necessity of immunomodulator administration considering an individual organism response to physical loads. 5 weeks after cessation of the training, in 75% of animals that were trained without correctrion, the signs of thymic involution (increase in the amount of adipose tissue, thickening of interlobular septae) were more expressed than in the animals of control group. In rats that received diucifon, thymus structure and cellular composition were similar to those in the control group.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1026-3543
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-8
pubmed:dateRevised
2011-5-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
[Morphological changes in the thymus during the physical loads applied simultaneously with the administration of diucifon and in the rehabilitation period].
pubmed:publicationType
Journal Article, English Abstract