Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2008-3-27
pubmed:abstractText
We have pioneered what we believe is a novel method of stimulating cochlear neurons, using pulsed infrared radiation, based on the hypothesis that optical radiation can provide more spatially selective stimulation of the cochlea than electric current. Very little of the available optical parameter space has been used for optical stimulation of neurons. Here, we use a pulsed diode laser (1.94 microm) to stimulate auditory neurons of the gerbil. Radiant exposures measured at CAP threshold are similar for pulse durations of 5, 10, 30, and 100 micros, but greater for 300-micros-long pulses. There is evidence that water absorption of optical radiation is a significant factor in optical stimulation. Heat-transfer-based analysis of the data indicates that potential structures involved in optical stimulation of cochlear neurons have a dimension on the order of approximately 10 microm. The implications of these data could direct further research and design of an optical cochlear implant.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-11519582, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-12141354, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-12509014, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-14523077, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-1487094, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-16158620, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-16409069, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-16871623, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-17477715, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-17496643, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-17526565, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-17554829, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-2373794, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-2613564, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-3400442, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-3624083, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-3654398, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-3840160, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-6814331, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-6836297, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-6892642, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-7405577, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-7472432, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-7830476, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-8207139, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-8234758, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-8735073, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-8793506, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-9176612, http://linkedlifedata.com/resource/pubmed/commentcorrection/18192375-9604350
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1542-0086
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3159-66
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Laser stimulation of auditory neurons: effect of shorter pulse duration and penetration depth.
pubmed:affiliation
Department of Otolaryngology, Northwestern University, Chicago, Illinois 60611, USA. a-izzo@northwestern.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural