Source:http://linkedlifedata.com/resource/pubmed/id/18191001
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2008-9-12
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pubmed:abstractText |
A series of phenylalanine derivatives were synthesized and their biological activities were evaluated. Compounds (S)-3 and (R)-3 exhibited more potent insulin-releasing activity than that of nateglinide, compound (S)-3 also showed insulin-sensitizing activity in vitro. Both compounds were tested for hypoglycemia effect in vivo.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0223-5234
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1997-2003
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18191001-Animals,
pubmed-meshheading:18191001-Cell Line,
pubmed-meshheading:18191001-Cricetinae,
pubmed-meshheading:18191001-Drug Design,
pubmed-meshheading:18191001-Hypoglycemic Agents,
pubmed-meshheading:18191001-Insulin,
pubmed-meshheading:18191001-Mice,
pubmed-meshheading:18191001-Phenylalanine
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pubmed:year |
2008
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pubmed:articleTitle |
Insulin-releasing activity of a series of phenylalanine derivatives.
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pubmed:affiliation |
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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