|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-4-3
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|
pubmed:abstractText |
Serotonin release from platelets is important for regulating hemostasis. Some prior studies suggest an association between use of selective serotonin reuptake inhibitors and gastrointestinal bleeding and a possible synergistic effect of these medications with non-steroidal anti-inflammatory drugs (NSAIDs). This study examined the effect of medications that inhibit serotonin uptake on upper gastrointestinal toxicity.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1099-1557
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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|
pubmed:volume |
17
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
328-35
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|
pubmed:meshHeading |
pubmed-meshheading:18188866-Adult,
pubmed-meshheading:18188866-Aged,
pubmed-meshheading:18188866-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:18188866-Antidepressive Agents,
pubmed-meshheading:18188866-Case-Control Studies,
pubmed-meshheading:18188866-Dose-Response Relationship, Drug,
pubmed-meshheading:18188866-Drug Synergism,
pubmed-meshheading:18188866-Female,
pubmed-meshheading:18188866-Hospital Records,
pubmed-meshheading:18188866-Hospitalization,
pubmed-meshheading:18188866-Humans,
pubmed-meshheading:18188866-International Classification of Diseases,
pubmed-meshheading:18188866-Interviews as Topic,
pubmed-meshheading:18188866-Logistic Models,
pubmed-meshheading:18188866-Male,
pubmed-meshheading:18188866-Middle Aged,
pubmed-meshheading:18188866-Peptic Ulcer Hemorrhage,
pubmed-meshheading:18188866-Risk Factors,
pubmed-meshheading:18188866-Serotonin Uptake Inhibitors
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
Moderate and high affinity serotonin reuptake inhibitors increase the risk of upper gastrointestinal toxicity.
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|
pubmed:affiliation |
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. jlewis@cceb.med.upenn.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
