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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-11
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pubmed:abstractText |
Mycobacterium leprae is an obligate intracellular pathogen. Ligand-binding is an important factor in the success of chemoprevention and chemotherapy. A new drug that can inhibit M. leprae binding to and activation of, ErbB2 and Erk1/2 in primary Schwann cells is the new therapeutic option. However, the ligand-binding pattern of ErbB2 has never been clarified.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0973-3922
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18187820-Binding Sites,
pubmed-meshheading:18187820-Computational Biology,
pubmed-meshheading:18187820-Drug Design,
pubmed-meshheading:18187820-Humans,
pubmed-meshheading:18187820-Leprosy,
pubmed-meshheading:18187820-Ligands,
pubmed-meshheading:18187820-Mycobacterium leprae,
pubmed-meshheading:18187820-Predictive Value of Tests,
pubmed-meshheading:18187820-Protein Binding,
pubmed-meshheading:18187820-Receptor, erbB-2,
pubmed-meshheading:18187820-Virulence
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pubmed:articleTitle |
Ligand-binding prediction for ErbB2, a key molecule in the pathogenesis of leprosy.
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pubmed:affiliation |
Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
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pubmed:publicationType |
Journal Article
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