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rdf:type |
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lifeskim:mentions |
umls-concept:C0018787,
umls-concept:C0021368,
umls-concept:C0035015,
umls-concept:C0086418,
umls-concept:C0178539,
umls-concept:C0205178,
umls-concept:C0332120,
umls-concept:C0439849,
umls-concept:C0450127,
umls-concept:C1144709,
umls-concept:C1301820,
umls-concept:C1548437,
umls-concept:C1882923
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-11
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pubmed:abstractText |
Cardiac natriuretic peptides (NPs) atrial natriuretic factor (ANF) and brain natriuretic peptide (BNP) are polypeptide hormones secreted by the heart. Previously, we found that BNP, but not ANF, plasma levels may increase during an acute cellular cardiac allograft rejection episode. In vitro, the pro-inflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) produced a selective increase of BNP gene expression and secretion. Other pro-inflammatory cytokines had no such effects.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1557-3117
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-7
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pubmed:meshHeading |
pubmed-meshheading:18187084-Acute Disease,
pubmed-meshheading:18187084-Adolescent,
pubmed-meshheading:18187084-Adult,
pubmed-meshheading:18187084-Aged,
pubmed-meshheading:18187084-Animals,
pubmed-meshheading:18187084-Animals, Newborn,
pubmed-meshheading:18187084-Atrial Natriuretic Factor,
pubmed-meshheading:18187084-Biopsy,
pubmed-meshheading:18187084-Cells, Cultured,
pubmed-meshheading:18187084-Cytokines,
pubmed-meshheading:18187084-Disease Progression,
pubmed-meshheading:18187084-Female,
pubmed-meshheading:18187084-Follow-Up Studies,
pubmed-meshheading:18187084-Graft Rejection,
pubmed-meshheading:18187084-Heart Catheterization,
pubmed-meshheading:18187084-Heart Transplantation,
pubmed-meshheading:18187084-Heart Ventricles,
pubmed-meshheading:18187084-Humans,
pubmed-meshheading:18187084-Male,
pubmed-meshheading:18187084-Middle Aged,
pubmed-meshheading:18187084-Myocytes, Cardiac,
pubmed-meshheading:18187084-Natriuretic Peptide, Brain,
pubmed-meshheading:18187084-Prognosis,
pubmed-meshheading:18187084-Radioimmunoassay,
pubmed-meshheading:18187084-Rats,
pubmed-meshheading:18187084-Severity of Illness Index,
pubmed-meshheading:18187084-Transplantation, Homologous
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pubmed:year |
2008
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pubmed:articleTitle |
Relationship between natriuretic peptides and inflammation: proteomic evidence obtained during acute cellular cardiac allograft rejection in humans.
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pubmed:affiliation |
Cardiovascular Endocrinology Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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