Source:http://linkedlifedata.com/resource/pubmed/id/18186611
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-2-25
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pubmed:abstractText |
The structure of an antiradical arabinoglucogalactan ( 1) from Panax notoginseng roots was determined. This polymeric carbohydrate was obtained through successive phosphate buffer (pH 7.0) extraction after cold-water pretreatment and purification by ion-exchange and gel-filtration chromatography. Monosaccharide analysis, permethylation analysis, NaIO 4 and CrO 3 oxidations, Smith degradation, graded acid hydrolysis, and IR and NMR experiments indicated that 1 possesses a backbone of (1-->3)-linked beta- d-galactofuranosyl residues, with branches of alpha- l-Ara f-(1-->4)-beta- d-Glc p-(1--> residues at O-6. Additionally, 1 exhibited high scavenging activity against DPPH free radicals with a 50% scavenging concentration (SC50) of 11.72 +/- 0.91 microg/mL, suggesting that this arabinoglucogalactan is a potential antiradical.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,2-diphenyl-1-picrylhydrazyl,
http://linkedlifedata.com/resource/pubmed/chemical/Biphenyl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radical Scavengers,
http://linkedlifedata.com/resource/pubmed/chemical/Galactans,
http://linkedlifedata.com/resource/pubmed/chemical/Picrates
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18186611-Biphenyl Compounds,
pubmed-meshheading:18186611-Carbohydrate Sequence,
pubmed-meshheading:18186611-Free Radical Scavengers,
pubmed-meshheading:18186611-Galactans,
pubmed-meshheading:18186611-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:18186611-Oxidation-Reduction,
pubmed-meshheading:18186611-Panax notoginseng,
pubmed-meshheading:18186611-Picrates,
pubmed-meshheading:18186611-Plant Roots,
pubmed-meshheading:18186611-Plants, Medicinal,
pubmed-meshheading:18186611-Stereoisomerism
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pubmed:year |
2008
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pubmed:articleTitle |
Structural characterization and DPPH radical scavenging activity of an arabinoglucogalactan from Panax notoginseng root.
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pubmed:affiliation |
Department of Chemistry, Columbia University, New York, New York 10027, USA. yw2248@columbia.edu
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pubmed:publicationType |
Journal Article
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