Linked Life Data

18184959

Source:http://linkedlifedata.com/resource/pubmed/id/18184959

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-1-10
pubmed:databankReference
pubmed:abstractText
Angiomyolipomas in patients with the tuberous sclerosis complex or sporadic lymphangioleiomyomatosis are associated with mutations in tuberous sclerosis genes resulting in constitutive activation of the mammalian target of rapamycin (mTOR). The drug sirolimus suppresses mTOR signaling.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1533-4406
pubmed:author
pubmed:copyrightInfo
2008 Massachusetts Medical Society
pubmed:issnType
Electronic
pubmed:day
10
pubmed:volume
358
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
140-51
pubmed:dateRevised
2010-12-3
pubmed:meshHeading
pubmed-meshheading:18184959-Adult, pubmed-meshheading:18184959-Angiomyolipoma, pubmed-meshheading:18184959-Brain, pubmed-meshheading:18184959-Female, pubmed-meshheading:18184959-Humans, pubmed-meshheading:18184959-Immunosuppressive Agents, pubmed-meshheading:18184959-Kidney Diseases, pubmed-meshheading:18184959-Liver Diseases, pubmed-meshheading:18184959-Lung, pubmed-meshheading:18184959-Lung Neoplasms, pubmed-meshheading:18184959-Lymphangioleiomyomatosis, pubmed-meshheading:18184959-Magnetic Resonance Imaging, pubmed-meshheading:18184959-Male, pubmed-meshheading:18184959-Middle Aged, pubmed-meshheading:18184959-Protein Kinase Inhibitors, pubmed-meshheading:18184959-Protein Kinases, pubmed-meshheading:18184959-Respiratory Function Tests, pubmed-meshheading:18184959-Sirolimus, pubmed-meshheading:18184959-TOR Serine-Threonine Kinases, pubmed-meshheading:18184959-Tuberous Sclerosis
pubmed:year
2008
pubmed:articleTitle
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.
pubmed:affiliation
Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. john.bissler@cchmc.org
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Clinical Trial, Phase II, Clinical Trial, Phase I, Research Support, N.I.H., Extramural