rdf:type |
|
lifeskim:mentions |
umls-concept:C0022131,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0056693,
umls-concept:C0061355,
umls-concept:C0079411,
umls-concept:C0205224,
umls-concept:C0283683,
umls-concept:C0596235,
umls-concept:C1256369,
umls-concept:C1710082
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-3-31
|
pubmed:abstractText |
Glucagon-like peptide-1 (GLP-1) increases intracellular Ca(2+) concentrations ([Ca(2+)](i)), resulting in insulin secretion from pancreatic beta-cells. The molecular mechanism(s) of the GLP-1-mediated regulation of [Ca(2+)](i) was investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD38,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic ADP-Ribose,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon-Like Peptide 1,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/NAADP,
http://linkedlifedata.com/resource/pubmed/chemical/NADP,
http://linkedlifedata.com/resource/pubmed/chemical/erythromycin...
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1939-327X
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
57
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
868-78
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:18184929-Acetylcysteine,
pubmed-meshheading:18184929-Animals,
pubmed-meshheading:18184929-Antigens, CD38,
pubmed-meshheading:18184929-Calcium,
pubmed-meshheading:18184929-Cyclic ADP-Ribose,
pubmed-meshheading:18184929-Endoplasmic Reticulum,
pubmed-meshheading:18184929-Erythromycin,
pubmed-meshheading:18184929-Glucagon-Like Peptide 1,
pubmed-meshheading:18184929-Insulin,
pubmed-meshheading:18184929-Islets of Langerhans,
pubmed-meshheading:18184929-Mice,
pubmed-meshheading:18184929-Mice, Inbred ICR,
pubmed-meshheading:18184929-Mice, Knockout,
pubmed-meshheading:18184929-NADP,
pubmed-meshheading:18184929-Signal Transduction
|
pubmed:year |
2008
|
pubmed:articleTitle |
Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets.
|
pubmed:affiliation |
Department of Biochemistry, Chonbuk National University Medical School, Keum-am dong, Jeonju, 561-182, Republic of Korea.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|