|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-1-10
|
|
pubmed:abstractText |
Nitric oxide (NO), produced by inducible NO synthase (iNOS), has been suggested to cause oxidative stress, leading to 8-hydroxydeoxyguanosine (8-OHdG) accumulation and subsequent transversion mutation of DNA. The aim was to evaluate iNOS expression and the status of oxidative stress in nasopharyngeal carcinoma (NPC).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/8-hydroxy-2'-deoxyguanosine,
http://linkedlifedata.com/resource/pubmed/chemical/Adaptor Proteins, Signal Transducing,
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyguanosine,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/LIM Domain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/PDLIM7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1365-2559
|
|
pubmed:author |
pubmed-author:HirakawaNN,
pubmed-author:KomuneSS,
pubmed-author:OdaYY,
pubmed-author:SegawaYY,
pubmed-author:ShiratsuchiHH,
pubmed-author:TomitaKK,
pubmed-author:TsuneyoshiMM,
pubmed-author:UryuHH,
pubmed-author:WUT MTM,
pubmed-author:YamadaTT,
pubmed-author:YamamotoHH,
pubmed-author:YamamotoTT
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
52
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
213-23
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:18184270-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:18184270-Adult,
pubmed-meshheading:18184270-Aged,
pubmed-meshheading:18184270-Aged, 80 and over,
pubmed-meshheading:18184270-Cytoskeletal Proteins,
pubmed-meshheading:18184270-DNA, Neoplasm,
pubmed-meshheading:18184270-DNA Damage,
pubmed-meshheading:18184270-Deoxyguanosine,
pubmed-meshheading:18184270-Female,
pubmed-meshheading:18184270-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18184270-Humans,
pubmed-meshheading:18184270-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:18184270-Kaplan-Meier Estimate,
pubmed-meshheading:18184270-LIM Domain Proteins,
pubmed-meshheading:18184270-Male,
pubmed-meshheading:18184270-Middle Aged,
pubmed-meshheading:18184270-Mutation,
pubmed-meshheading:18184270-Nasopharyngeal Neoplasms,
pubmed-meshheading:18184270-Neoplasms, Squamous Cell,
pubmed-meshheading:18184270-Nitric Oxide Synthase Type II,
pubmed-meshheading:18184270-Oxidative Stress,
pubmed-meshheading:18184270-RNA, Messenger,
pubmed-meshheading:18184270-RNA, Viral,
pubmed-meshheading:18184270-Tumor Suppressor Protein p53
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Overexpression of inducible nitric oxide synthase and accumulation of 8-OHdG in nasopharyngeal carcinoma.
|
|
pubmed:affiliation |
Department of Anatomic Pathology, and Department of Otolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
