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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-7-10
|
| pubmed:abstractText |
The results of preclinical trials of 28 new compounds of haloid-containing sulfamidobenzamides with low toxicity are presented. The trials on a hymenolepiasis model showed that effectiveness of N-(2,5-dichlorophenyl)-2/(3-nitro-4-chlorophenyl) sulfonylamino/-5-bromobenzamide was similar to that of the well-known drug niclosamide. In the trials on an opisthorchiasis model, 2 compounds were shown to be highly effective, and on a trichocephaliasis model 5 compounds showed a high activity.
|
| pubmed:language |
rus
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0025-8326
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
52-3
|
| pubmed:dateRevised |
2009-10-21
|
| pubmed:meshHeading |
pubmed-meshheading:1818252-Animals,
pubmed-meshheading:1818252-Anthelmintics,
pubmed-meshheading:1818252-Benzamides,
pubmed-meshheading:1818252-Drug Evaluation, Preclinical,
pubmed-meshheading:1818252-Halogens,
pubmed-meshheading:1818252-Helminthiasis,
pubmed-meshheading:1818252-Structure-Activity Relationship,
pubmed-meshheading:1818252-Sulfonamides
|
| pubmed:articleTitle |
[The search for new antiparasitic agents. 9. The anthelmintic activity of halogen-containing sulfonamidobenzamides].
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|