Linked Life Data

18180353

Source:http://linkedlifedata.com/resource/pubmed/id/18180353

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pubmed-article:18180353pubmed:abstractTextTwo investigational anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) beta-lactams, ceftaroline (a cephalosporin) and ME1036 (a carbapenem), were subjected to susceptibility testing by reference broth microdilution methods using 152 strains of community-acquired MRSA from the United States (47 medical centers). Ceftaroline and ME1036 were 64- and >128-fold more potent than ceftriaxone, respectively. All isolates had the Panton-Valentine leukocidin genes and staphylococcal cassette chromosome mec type IV, while 67.8% of isolates displayed pulsed-field gel electrophoresis clonal type USA300-0114.lld:pubmed
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pubmed-article:18180353pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:18180353pubmed:articleTitleAntimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus.lld:pubmed
pubmed-article:18180353pubmed:affiliationJMI Laboratories, 345 Beaver Kreek Centre, Suite A, North Liberty, IA 52317, USA. helio-sader@jmilabs.comlld:pubmed
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pubmed-article:18180353pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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