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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-26
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pubmed:abstractText |
Two investigational anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) beta-lactams, ceftaroline (a cephalosporin) and ME1036 (a carbapenem), were subjected to susceptibility testing by reference broth microdilution methods using 152 strains of community-acquired MRSA from the United States (47 medical centers). Ceftaroline and ME1036 were 64- and >128-fold more potent than ceftriaxone, respectively. All isolates had the Panton-Valentine leukocidin genes and staphylococcal cassette chromosome mec type IV, while 67.8% of isolates displayed pulsed-field gel electrophoresis clonal type USA300-0114.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-10524952,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-15273088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-15290453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-15856382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-16048970,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-16390957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-16520471,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-17391376,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-17548456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-17576837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-17591849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18180353-9709046
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0066-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1153-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18180353-Anti-Bacterial Agents,
pubmed-meshheading:18180353-Carbapenems,
pubmed-meshheading:18180353-Cephalosporins,
pubmed-meshheading:18180353-Community-Acquired Infections,
pubmed-meshheading:18180353-Humans,
pubmed-meshheading:18180353-Methicillin Resistance,
pubmed-meshheading:18180353-Microbial Sensitivity Tests,
pubmed-meshheading:18180353-Staphylococcal Infections,
pubmed-meshheading:18180353-Staphylococcus aureus,
pubmed-meshheading:18180353-United States,
pubmed-meshheading:18180353-beta-Lactams
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pubmed:year |
2008
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pubmed:articleTitle |
Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus.
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pubmed:affiliation |
JMI Laboratories, 345 Beaver Kreek Centre, Suite A, North Liberty, IA 52317, USA. helio-sader@jmilabs.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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