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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-16
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pubmed:abstractText |
Several studies suggest that the evolutionary rate of HVR1 sequence in acute HCV hepatitis derives from the action of a continuous immune-driven positive selection. However, these studies have not been performed examining the relationship between HVR1 evolution and the development of specific immunity to autologous HVR1 sequences.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:Acute Hepatitis C Italian Study Group,
pubmed-author:CapobianchiMaria RosariaMR,
pubmed-author:Del PortoPaolaP,
pubmed-author:FolgoriAntonellaA,
pubmed-author:GarbugliaAnna RosaAR,
pubmed-author:GirelliGabriellaG,
pubmed-author:LaurentiLucaL,
pubmed-author:MeleAlfonsoA,
pubmed-author:NicosiaAlfredoA,
pubmed-author:PerroneMaria PaolaMP,
pubmed-author:PiccolellaEnzaE,
pubmed-author:RuggeriLionelloL,
pubmed-author:ScottàCristianoC,
pubmed-author:SpadaEneaE
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
216-28
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18180071-Acute Disease,
pubmed-meshheading:18180071-Adult,
pubmed-meshheading:18180071-Amino Acid Sequence,
pubmed-meshheading:18180071-CD4-Positive T-Lymphocytes,
pubmed-meshheading:18180071-Evolution, Molecular,
pubmed-meshheading:18180071-Female,
pubmed-meshheading:18180071-Genetic Variation,
pubmed-meshheading:18180071-Hepatitis C,
pubmed-meshheading:18180071-Hepatitis C Antibodies,
pubmed-meshheading:18180071-Humans,
pubmed-meshheading:18180071-Longitudinal Studies,
pubmed-meshheading:18180071-Male,
pubmed-meshheading:18180071-Middle Aged,
pubmed-meshheading:18180071-Molecular Sequence Data,
pubmed-meshheading:18180071-Viral Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Influence of specific CD4+ T cells and antibodies on evolution of hypervariable region 1 during acute HCV infection.
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pubmed:affiliation |
Department of Cellular and Developmental Biology,"La Sapienza" University of Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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