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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-3-17
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pubmed:abstractText |
A potent sigma-2 receptor ligand, known as PB28, was tritium radiolabelled and biologically evaluated. The results showed that [(3)H]PB28 and the corresponding unlabelled PB28 had superimposed pharmacodynamic properties. This radioligand appears as a potential candidate for receptor binding and in living cells assays.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1464-3405
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2183-7
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pubmed:meshHeading |
pubmed-meshheading:18178434-Animals,
pubmed-meshheading:18178434-Binding, Competitive,
pubmed-meshheading:18178434-Binding Sites,
pubmed-meshheading:18178434-Cell Membrane,
pubmed-meshheading:18178434-Liver,
pubmed-meshheading:18178434-Molecular Structure,
pubmed-meshheading:18178434-Piperazines,
pubmed-meshheading:18178434-RNA, Messenger,
pubmed-meshheading:18178434-Radioligand Assay,
pubmed-meshheading:18178434-Rats,
pubmed-meshheading:18178434-Receptors, sigma,
pubmed-meshheading:18178434-Tritium
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pubmed:year |
2008
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pubmed:articleTitle |
Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization.
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pubmed:affiliation |
Dipartimento Farmacochimico, Università degli Studi di Bari, via Orabona 4, 70125 Bari, Italy. colabufo@farmchim.uniba.it
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pubmed:publicationType |
Journal Article
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