Source:http://linkedlifedata.com/resource/pubmed/id/18177007
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-1-28
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pubmed:abstractText |
An investigation of the Phillippine Ampelocissus sp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin (1) employing primarily 2D NMR and high-resolution mass spectral analysis. Two other antineoplastic constituents proved to be the known acetogenin uvaribonin (2) and chalcone 3. Constituents 1-3 were all found to show significant cancer cell growth inhibitory activity against a panel of human cancer cell lines.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
130-3
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pubmed:meshHeading |
pubmed-meshheading:18177007-Acetogenins,
pubmed-meshheading:18177007-Animals,
pubmed-meshheading:18177007-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:18177007-Crystallography, X-Ray,
pubmed-meshheading:18177007-Drug Screening Assays, Antitumor,
pubmed-meshheading:18177007-Humans,
pubmed-meshheading:18177007-Male,
pubmed-meshheading:18177007-Molecular Conformation,
pubmed-meshheading:18177007-Molecular Structure,
pubmed-meshheading:18177007-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:18177007-Vitaceae
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pubmed:year |
2008
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pubmed:articleTitle |
Antineoplastic agents. 558. Ampelocissus sp. cancer cell growth inhibitory constituents.
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pubmed:affiliation |
Cancer Research Institute and Department of Chemistry and Biochemistry, Arizona State University, Tempe 85287-2404, USA. bpettit@asu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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