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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-4
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pubmed:abstractText |
Preeclampsia is considered an anti-angiogenic state. A role for the anti-angiogenic factors soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) and soluble endoglin in preeclampsia has been proposed. Soluble vascular endothelial growth factor receptor-2 (sVEGFR-2) has been detected in human plasma, and the recombinant form of this protein has anti-angiogenic activity. There is a paucity of information about maternal plasma sVEGFR-2 concentrations in patients with preeclampsia and those without preeclampsia with small for gestational age (SGA) fetuses. This study was conducted to determine whether: (1) plasma sVEGFR-2 concentration changes throughout pregnancy; and (2) preeclampsia and SGA are associated with abnormalities in the maternal plasma concentration of sVEGFR-2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1476-7058
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pubmed:author |
pubmed-author:ChaiworapongsaTinnakornT,
pubmed-author:EdwinSamuelS,
pubmed-author:ErezOfferO,
pubmed-author:EspinozaJimmyJ,
pubmed-author:GoncalvesLuisL,
pubmed-author:GotschFrancescaF,
pubmed-author:HassanSoniaS,
pubmed-author:KimYeon MeeYM,
pubmed-author:KusanovicJuan PedroJP,
pubmed-author:NienJyh KaeJK,
pubmed-author:PappZoltanZ,
pubmed-author:PinelesBeth LBL,
pubmed-author:RomeroRobertoR
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
41-52
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18175243-Adolescent,
pubmed-meshheading:18175243-Adult,
pubmed-meshheading:18175243-Case-Control Studies,
pubmed-meshheading:18175243-Cross-Sectional Studies,
pubmed-meshheading:18175243-Female,
pubmed-meshheading:18175243-Fetal Growth Retardation,
pubmed-meshheading:18175243-Humans,
pubmed-meshheading:18175243-Infant, Newborn,
pubmed-meshheading:18175243-Infant, Small for Gestational Age,
pubmed-meshheading:18175243-Pre-Eclampsia,
pubmed-meshheading:18175243-Pregnancy,
pubmed-meshheading:18175243-Retrospective Studies,
pubmed-meshheading:18175243-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2008
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pubmed:articleTitle |
Low maternal concentrations of soluble vascular endothelial growth factor receptor-2 in preeclampsia and small for gestational age.
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pubmed:affiliation |
Perinatology Research Branch, National Institute of Child Health and Human Development, NIH/DHHS, Bethesda, MD 20892, USA.
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pubmed:publicationType |
Journal Article
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