rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-4
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pubmed:abstractText |
Recent data indicate that statins could offer coronary artery disease (CAD) benefit even by mechanisms beyond lipid lowering. Genetic influence has been shown for some antithrombotic actions of statins via oxidized-low-density lipoprotein cholesterol (ox-LDL) receptors and nitric oxide synthase (NOS) activity modulation. The present study was designed to evaluate the influence of ox-LDL lectin-like receptor-1 (LOX-1) and NOS polymorphisms in the incidence of cardiovascular events in pure hypercholesterolaemic subjects during statin treatment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anticholesteremic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrinolytic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Heptanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/OLR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class E,
http://linkedlifedata.com/resource/pubmed/chemical/atorvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1365-2362
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-6
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pubmed:meshHeading |
pubmed-meshheading:18173546-Adolescent,
pubmed-meshheading:18173546-Adult,
pubmed-meshheading:18173546-Aged,
pubmed-meshheading:18173546-Anticholesteremic Agents,
pubmed-meshheading:18173546-Coronary Artery Disease,
pubmed-meshheading:18173546-Female,
pubmed-meshheading:18173546-Fibrinolytic Agents,
pubmed-meshheading:18173546-Heptanoic Acids,
pubmed-meshheading:18173546-Humans,
pubmed-meshheading:18173546-Hypercholesterolemia,
pubmed-meshheading:18173546-Lipoproteins, LDL,
pubmed-meshheading:18173546-Male,
pubmed-meshheading:18173546-Middle Aged,
pubmed-meshheading:18173546-Nitric Oxide Synthase,
pubmed-meshheading:18173546-Polymorphism, Genetic,
pubmed-meshheading:18173546-Pyrroles,
pubmed-meshheading:18173546-Scavenger Receptors, Class E
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pubmed:year |
2008
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pubmed:articleTitle |
Genetic influence in antithrombotic actions of atorvastatin in hypercholesterolaemia.
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pubmed:affiliation |
Department of Clinical Medicine and Immunology, Internal Medicine Division, Centre for Atherosclerosis Research, University of Siena, Siena, Italy. puccetti@unisi.it
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pubmed:publicationType |
Journal Article,
Clinical Trial
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