Although the apolipoprotein (APOE)-epsilon4 allele has been shown to determine the outcome of several infections, its relationship with cytomegalovirus (CMV) has not been explored. We examine whether APOE determines CMV and herpes simplex virus type 1 (HSV-1) antibody levels and assess whether C-reactive protein (CRP) mediates any observed relationships.
Dept. of Epidemiology, Center for Social Epidemiology and Population Health, University of Michigan School of Public Health, 3659 SPH Tower, 109 Observatory, Ann Arbor, MI 48109-2029, USA. aielloa@umich.edu
