|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2008-1-1
|
|
pubmed:abstractText |
Fifty to sixty percent of patients with essential thrombocythemia harbor the JAK2(V617F) mutation. The impact of this mutation on clinical phenotype is still debated. The aim of this study was to evaluate possible correlations between JAK2(V617F) mutant allele burden and both clinical presentation and hematologic abnormalities in essential thrombocythemia patients.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1592-8721
|
|
pubmed:author |
pubmed-author:AntonioliElisabettaE,
pubmed-author:BoganiCostanzaC,
pubmed-author:BosiAlbertoA,
pubmed-author:GuglielmelliPaolaP,
pubmed-author:LongoGiovanniG,
pubmed-author:Myeloproliferative Disorders Research Consortium (MPD-RC),
pubmed-author:PancrazziAlessandroA,
pubmed-author:PieriLisaL,
pubmed-author:PoliGiadaG,
pubmed-author:PonzianiVanessaV,
pubmed-author:SantiniValeriaV,
pubmed-author:TozziLorenzoL,
pubmed-author:VannucchiAlessandro MAM
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
93
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
41-8
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:18166784-Adolescent,
pubmed-meshheading:18166784-Adult,
pubmed-meshheading:18166784-Aged,
pubmed-meshheading:18166784-Aged, 80 and over,
pubmed-meshheading:18166784-Alleles,
pubmed-meshheading:18166784-Female,
pubmed-meshheading:18166784-Granulocytes,
pubmed-meshheading:18166784-Humans,
pubmed-meshheading:18166784-Janus Kinase 2,
pubmed-meshheading:18166784-Male,
pubmed-meshheading:18166784-Middle Aged,
pubmed-meshheading:18166784-Phenotype,
pubmed-meshheading:18166784-Retrospective Studies,
pubmed-meshheading:18166784-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18166784-Thrombocythemia, Essential
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia.
|
|
pubmed:affiliation |
Department of Hematology, University of Florence, 50134, Florence, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
