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pubmed:abstractText |
Atrichia with papular lesions (APL) (OMIM#209500) is a rare autosomal recessively inherited form of irreversible alopecia characterized by papular lesions of keratin-filled cysts on various regions of the body. Males and females are equally affected and present with a distinct pattern of total hair loss on scalp, axilla and body. It begins shortly after birth with the development of hair loss, and patients are normally devoid of eyelashes and eyebrows. Mutations in the hairless (HR) gene have been previously shown to be responsible for APL.
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pubmed:affiliation |
Department of Dermatology, Columbia University, College of Physicians & Surgeons, 630 West 168th Street VC15 204A, New York, NY 10032, USA.
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