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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-21
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pubmed:abstractText |
Type IX collagen is an important component of the intervertebral disc extracellular matrix. Mutations in type IX collagen are associated with premature disc degeneration in mice and a predisposition to disc disorders in humans. The aim of this study was to assess the prevalence and timeline of intervertebral disc degeneration in mice homozygous for an inactivated Col9a1 gene.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
164-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18163498-Age of Onset,
pubmed-meshheading:18163498-Animals,
pubmed-meshheading:18163498-Collagen Type IX,
pubmed-meshheading:18163498-Disease Models, Animal,
pubmed-meshheading:18163498-Extracellular Matrix,
pubmed-meshheading:18163498-Female,
pubmed-meshheading:18163498-Homozygote,
pubmed-meshheading:18163498-Intervertebral Disc,
pubmed-meshheading:18163498-Intervertebral Disc Displacement,
pubmed-meshheading:18163498-Male,
pubmed-meshheading:18163498-Mice,
pubmed-meshheading:18163498-Mice, Inbred C57BL,
pubmed-meshheading:18163498-Mice, Knockout,
pubmed-meshheading:18163498-Thoracic Vertebrae
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pubmed:year |
2008
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pubmed:articleTitle |
Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen.
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pubmed:affiliation |
Duke University, Durham, North Carolina 27708, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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