Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-1-8
pubmed:abstractText
The purpose of this work was to demonstrate production by the Candida yeasts growing as a biofilm of a compound that reduces candidal biofilm growth. An in vitro model of Candida albicans biofilm associated with silicone catheters was used. Supernatant medium recovered from 24-h-old C. albicans (ATCC 3153) biofilm (S24h) was added during the course of new biofilm formation by four C. albicans strains (182, 444, 2091 or ATCC 3153). Addition of S24h to adherent C. albicans cells induced an inhibition of biofilm growth (P<0.001) but displayed no activity on established biofilms. Ultrafiltration and purification assays demonstrated that the antagonistic molecule is hydrophilic and <3000Da in size.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0924-8579
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
166-70
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm.
pubmed:affiliation
Equipe de Parasitologie et Mycologie Médicales, LCEE, Université de Poitiers, UMR 6008, 6 Rue de la Milètrie, BP 199, 86034 Poitiers cedex et CHU de Poitiers, France. estellecateau@msn.com
pubmed:publicationType
Journal Article