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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-26
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pubmed:abstractText |
Changes of the adenosine A(3) receptor subtype (A3AR) expression have been shown in a variety of pathologies, especially neurological and affective disorders, cardiac diseases and oncological and inflammation processes. Recently, 5-(2-fluoroethyl) 2,4-diethyl-3-(ethylsulfanylcarbonyl)-6-phenylpyridine-5-carboxylate (FE@SUPPY) was presented as a high-affinity ligand for the A3AR with good selectivity. Our aims were the development of a suitable labeling precursor, the establishment of a reliable radiosynthesis for the fluorine-18-labeled analogue [(18)F]FE@SUPPY and a first evaluation of [(18)F]FE@SUPPY in rats.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0969-8051
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pubmed:author |
pubmed-author:DudczakRobertR,
pubmed-author:EttlingerDagmar EDE,
pubmed-author:HaeuslerDanielaD,
pubmed-author:KepplerBernhard KBK,
pubmed-author:KletterKurtK,
pubmed-author:LanzenbergerRupert RRR,
pubmed-author:MienLeonhard-KeyLK,
pubmed-author:MitterhauserMarkusM,
pubmed-author:ShanabKaremK,
pubmed-author:SindelarKarolineK,
pubmed-author:SpreitzerHelmutH,
pubmed-author:ViernsteinHelmutH,
pubmed-author:WadsakWolfgangW
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-6
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pubmed:dateRevised |
2011-4-6
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pubmed:meshHeading |
pubmed-meshheading:18158944-Animals,
pubmed-meshheading:18158944-Autoradiography,
pubmed-meshheading:18158944-Fluorine Radioisotopes,
pubmed-meshheading:18158944-Male,
pubmed-meshheading:18158944-Nicotinic Acids,
pubmed-meshheading:18158944-Positron-Emission Tomography,
pubmed-meshheading:18158944-Radiopharmaceuticals,
pubmed-meshheading:18158944-Rats,
pubmed-meshheading:18158944-Rats, Sprague-Dawley,
pubmed-meshheading:18158944-Rats, Wistar,
pubmed-meshheading:18158944-Receptor, Adenosine A3,
pubmed-meshheading:18158944-Tissue Distribution
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pubmed:year |
2008
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pubmed:articleTitle |
Preparation and first evaluation of [(18)F]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor.
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pubmed:affiliation |
Department of Nuclear Medicine, Medical University of Vienna, A-1090 Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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