Linked Life Data

1815714

Source:http://linkedlifedata.com/resource/pubmed/id/1815714

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-7-2
pubmed:abstractText
Tooth whitening systems are widely used clinically and for home usage. The aim of this study was to determine the effects of two bleaching gels, each containing 10 percent and 15 percent carbamide peroxide, respectively, a 'bleaching gel' without carbamide peroxide, and carbamide peroxide alone on the viability of human endothelial cells in vitro in comparison with culture medium that acted as a negative control. The incubation period used was 30 minutes. A colorimetric viability assay (MTT assay) was employed. The results showed that the gel without carbamide peroxide is not cytotoxic compared to the negative control, while carbamide peroxide on its own and 10 percent and 15 percent carbamide peroxide bleaching gels were cytotoxic, but there were no significant differences (p greater than 0.05) among these latter three test groups. These data indicate that 10 percent and 15 percent carbamide peroxide bleaching gels are cytotoxic and that carbamide peroxide is the component responsible for this cytotoxic effect. This paper also discusses why this in vitro cytotoxic effect appears not to be significant in vivo.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1040-1466
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
162-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Is home tooth bleaching gel cytotoxic?
pubmed:affiliation
London Hospital Medical College.
pubmed:publicationType
Journal Article