Source:http://linkedlifedata.com/resource/pubmed/id/18156379
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2007-12-24
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pubmed:abstractText |
Glucocorticoids have an important role in the regulation of the immune system, and alterations in glucocorticoid signaling may have an impact on the pathophysiology of autoimmune and inflammatory disorders. Because polymorphisms of the glucocorticoid receptor (GR) gene, including the N363S, ER22/23EK, A3669G and BclI variants were found to influence glucocorticoid signalling, we examined whether these polymorphisms could be associated with the development or clinical manifestations of Graves ophthalmopathy (GO).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1468-2079
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131-4
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pubmed:dateRevised |
2008-5-28
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pubmed:meshHeading |
pubmed-meshheading:18156379-Adult,
pubmed-meshheading:18156379-Aged,
pubmed-meshheading:18156379-Female,
pubmed-meshheading:18156379-Gene Frequency,
pubmed-meshheading:18156379-Graves Ophthalmopathy,
pubmed-meshheading:18156379-Heterozygote,
pubmed-meshheading:18156379-Humans,
pubmed-meshheading:18156379-Male,
pubmed-meshheading:18156379-Middle Aged,
pubmed-meshheading:18156379-Polymorphism, Genetic,
pubmed-meshheading:18156379-Receptors, Glucocorticoid,
pubmed-meshheading:18156379-Severity of Illness Index
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pubmed:year |
2008
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pubmed:articleTitle |
Polymorphisms of the glucocorticoid receptor gene in Graves ophthalmopathy.
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pubmed:affiliation |
Second Department of Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary. belema.boyle@gmail.com
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pubmed:publicationType |
Journal Article,
Multicenter Study
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