Linked Life Data

1811438

Source:http://linkedlifedata.com/resource/pubmed/id/1811438

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-5-29
pubmed:abstractText
Enzyme linked immunosorbent assay (ELISA), dot immunobinding assay (DIA) and passive haemagglutination assay (PHA) were evaluated for the detection of anticysticercal antibodies in cerebrospinal fluids (CSF) from neurocysticercosis (NCC) patients. Results from the three tests were similar. Higher titres of antibodies were observed to the antigens in porcine whole-cyst sonicate than to those in vesicular fluid or scolex or membrane sonicates. Affinity purified parasitic antigens showed a higher degree of specificity and sensitivity in PHA than in ELISA or DIA. Western blot analyses with cyst antigens showed that CSF antibodies from confirmed NCC patients consistently recognized a protein in the region of 64-68 kDa. Other proteins, of 110, 94-97, 80, 72-75, 52, 45, 26-28 and 16-18 kDa, showed heterogenous reactivity, whereas the partially purified antigen of 64-68 kDa showed a high degree of sensitivity and specificity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
605-15
pubmed:dateRevised
2009-5-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Comparative evaluation of cysticercal antigens and immunoassays in the diagnosis of neurocysticercosis.
pubmed:affiliation
Department of Medical Microbiology and Immunology, National Institute of Mental Health and Neurosciences, Bangalore, India.
pubmed:publicationType
Journal Article, Comparative Study