Linked Life Data

1809521

Source:http://linkedlifedata.com/resource/pubmed/id/1809521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-5-26
pubmed:abstractText
A low-molecular leukocyte dialysate, suppressor transfer factor (STF), exerting a stimulating effect on CD8 subpopulations in man, was administered to 17 patients with amyotrophic lateral sclerosis (ALS). Following three s.c. injections of STF, activation of CD8 subpopulations was noted in 11 patients while a decrease in CD4 in seven. Progression of the disease was found to slow in nine outpatients administered STF injections at an interval of 3-4 weeks. No therapeutic effect was seen in four patients in whom STF injection failed to show stimulating activity on lymphocyte subpopulations. Remission of the stimulating effect of STF occurs within four weeks. No side effects were seen in any of the patients treated. The effect of STF on immune reactivity and on the clinical course of ALS supports the hypothesis of autoimmune character of the disease.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0301-0597
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Low-molecular transfer factor and its use in the treatment of amyotrophic lateral sclerosis].
pubmed:affiliation
Neurologická klinika 1. Lék. Fak. UK, Praha.
pubmed:publicationType
Journal Article, English Abstract