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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-12-20
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pubmed:abstractText |
Cellular drug resistance is supposed to play a major role in chemotherapy failure or relapse. The purpose of this study was to analyze the relationship between in vitro chemosensitivity test results using a 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and clinical response on chemotherapy, and to find the possibility of optimizing the treatment protocol for individual patients according to their actual drug resistance.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1598-6535
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-95
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pubmed:meshHeading |
pubmed-meshheading:18094557-Adolescent,
pubmed-meshheading:18094557-Adult,
pubmed-meshheading:18094557-Aged,
pubmed-meshheading:18094557-Aged, 80 and over,
pubmed-meshheading:18094557-Antibiotics, Antineoplastic,
pubmed-meshheading:18094557-Child,
pubmed-meshheading:18094557-Child, Preschool,
pubmed-meshheading:18094557-Coloring Agents,
pubmed-meshheading:18094557-Cytarabine,
pubmed-meshheading:18094557-Daunorubicin,
pubmed-meshheading:18094557-Drug Evaluation, Preclinical,
pubmed-meshheading:18094557-Drug Resistance, Neoplasm,
pubmed-meshheading:18094557-Female,
pubmed-meshheading:18094557-Humans,
pubmed-meshheading:18094557-Infant,
pubmed-meshheading:18094557-Leukemia, Biphenotypic, Acute,
pubmed-meshheading:18094557-Leukemia, Myeloid, Acute,
pubmed-meshheading:18094557-Male,
pubmed-meshheading:18094557-Middle Aged,
pubmed-meshheading:18094557-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:18094557-Tetrazolium Salts,
pubmed-meshheading:18094557-Thiazoles,
pubmed-meshheading:18094557-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
Relationship between in vitro chemosensitivity assessed with MTT assay and clinical outcomes in 103 patients with acute leukemia.
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pubmed:affiliation |
Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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