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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0458003,
umls-concept:C0678723,
umls-concept:C1171892,
umls-concept:C1235660,
umls-concept:C1254042,
umls-concept:C1522318,
umls-concept:C1710082,
umls-concept:C2911684
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2008-4-14
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|
pubmed:abstractText |
Currently, many potential cardiac revascularization therapies target the vascular endothelial growth factor (VEGF) pathway, with variable success. Knowledge regarding the role of the VEGF/Notch/ephrinB2 cascade in (ab)normal coronary development will provide information on the subtle balance of VEGF signalling in coronary maturation and might enhance our therapeutic possibilities.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
|
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pubmed:issn |
0008-6363
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
78
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
366-75
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pubmed:meshHeading |
pubmed-meshheading:18093989-Animals,
pubmed-meshheading:18093989-Cell Differentiation,
pubmed-meshheading:18093989-Cells, Cultured,
pubmed-meshheading:18093989-Coronary Vessels,
pubmed-meshheading:18093989-Endothelial Cells,
pubmed-meshheading:18093989-Ephrin-B2,
pubmed-meshheading:18093989-Gene Expression Regulation, Developmental,
pubmed-meshheading:18093989-Heart,
pubmed-meshheading:18093989-Humans,
pubmed-meshheading:18093989-Immunohistochemistry,
pubmed-meshheading:18093989-Mice,
pubmed-meshheading:18093989-Mice, Transgenic,
pubmed-meshheading:18093989-Myocardium,
pubmed-meshheading:18093989-Neovascularization, Physiologic,
pubmed-meshheading:18093989-Protein Isoforms,
pubmed-meshheading:18093989-RNA, Messenger,
pubmed-meshheading:18093989-Receptors, Notch,
pubmed-meshheading:18093989-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18093989-Signal Transduction,
pubmed-meshheading:18093989-Time Factors,
pubmed-meshheading:18093989-Vascular Endothelial Growth Factor A,
pubmed-meshheading:18093989-Vascular Endothelial Growth Factors,
pubmed-meshheading:18093989-Veins
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pubmed:year |
2008
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pubmed:articleTitle |
Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.
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pubmed:affiliation |
Department of Anatomy and Embryology, Leiden University Medical Center, Einthovenweg 20, PO Box 9600, 2300 RC Leiden, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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