Linked Life Data

18093622

Source:http://linkedlifedata.com/resource/pubmed/id/18093622

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-2-25
pubmed:abstractText
In addition to the seminal lesion studies of aphasiology, the development of functional neuroimaging has allowed a better understanding of the neural foundations of language. However, despite a substantial improvement in the knowledge of the cortical networks organization, the underlying subcortical association circuits have received less attention. Recent advances in fiber tracking using diffusion tensor imaging, combined with personal studies using intraoperative electrostimulation, which temporarily inactivates restricted regions during brain surgery, have enabled to map language pathways in humans with spatiotemporal resolution unmatched by other techniques. On the basis of these new insights, my purpose is to revisit the anatomo-functional connectivity of language. First, I discuss the role of the white bundles thought to be essential for language, with special emphasis regarding the structure-function relationships pertaining to the distinct subcomponents of language. Second, I propose an integrative view of connectivity, that considers language as the final product of the well-synchronized functioning of parallel distributed cortico-subcortical networks.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0028-3932
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
927-34
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The anatomo-functional connectivity of language revisited. New insights provided by electrostimulation and tractography.
pubmed:affiliation
Department of Neurosurgery, Hôpital Gui de Chauliac, CHU de Montpellier, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France. h-duffau@chu-montpellier.fr
pubmed:publicationType
Journal Article, Review