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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-4
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pubmed:abstractText |
We examined the presence of functional cannabinoid receptors 1 and 2 (CB1, CB2) in isolated human islets, phenotyped the cells producing cannabinoid receptors and analysed the actions of selective cannabinoid receptor agonists on insulin, glucagon and somatostatin secretion in vitro. We also described the localisation on islet cells of: (1) the endocannabinoid-producing enzymes N-acyl-phosphatidyl ethanolamine-hydrolysing phospholipase D and diacylglycerol lipase; and (2) the endocannabinoid-degrading enzymes fatty acid amidohydrolase and monoacyl glycerol lipase.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0012-186X
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pubmed:author |
pubmed-author:BaixerasEE,
pubmed-author:BautistaDD,
pubmed-author:Bermúdez-SilvaF JFJ,
pubmed-author:CastroM JMJ,
pubmed-author:CoboNN,
pubmed-author:Cuesta-MuñozA LAL,
pubmed-author:FuentesEE,
pubmed-author:Juan-PicoPP,
pubmed-author:MechoulamRR,
pubmed-author:MilmanGG,
pubmed-author:NadalAA,
pubmed-author:Rodríguez de FonsecaFF,
pubmed-author:SuárezJJ
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pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
476-87
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pubmed:meshHeading |
pubmed-meshheading:18092149-Brain Death,
pubmed-meshheading:18092149-Cannabinoids,
pubmed-meshheading:18092149-Cerebellum,
pubmed-meshheading:18092149-Glucagon,
pubmed-meshheading:18092149-Humans,
pubmed-meshheading:18092149-Insulin-Secreting Cells,
pubmed-meshheading:18092149-Islets of Langerhans,
pubmed-meshheading:18092149-Leukocytes,
pubmed-meshheading:18092149-Polymerase Chain Reaction,
pubmed-meshheading:18092149-RNA, Messenger,
pubmed-meshheading:18092149-Receptor, Cannabinoid, CB1,
pubmed-meshheading:18092149-Receptor, Cannabinoid, CB2,
pubmed-meshheading:18092149-Somatostatin-Secreting Cells,
pubmed-meshheading:18092149-Synaptic Transmission
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pubmed:year |
2008
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pubmed:articleTitle |
Presence of functional cannabinoid receptors in human endocrine pancreas.
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pubmed:affiliation |
Fundación IMABIS, Hospital Carlos Haya, Avenida Carlos Haya 82, 7a Planta, Pabellón A, 29010 Málaga, Spain. franciscoj.bermudez@fundacionimabis.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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