| pubmed-article:18090506 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18090506 | lifeskim:mentions | umls-concept:C0013227 | lld:lifeskim |
| pubmed-article:18090506 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:18090506 | lifeskim:mentions | umls-concept:C0003289 | lld:lifeskim |
| pubmed-article:18090506 | lifeskim:mentions | umls-concept:C1269683 | lld:lifeskim |
| pubmed-article:18090506 | lifeskim:mentions | umls-concept:C0009563 | lld:lifeskim |
| pubmed-article:18090506 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:18090506 | pubmed:dateCreated | 2007-12-19 | lld:pubmed |
| pubmed-article:18090506 | pubmed:abstractText | The investigation of compliance in patients with major depressive disorder (in drop-outs versus completers and in first episode versus recurrent episode patients). A total of 85 outpatients with major depressive disorder were followed for 6 months. Different dimensions of compliance were investigated: drop-outs versus completers and their medication adherence (with electronic monitoring). General linear mixed models were applied to examine the time courses of adherence. Drop-out rates were higher in younger patients and in patients with a lower initial depression severity. The adherence during 6 months of treatment with selective serotonin reuptake inhibitors was above 80 in 70% of the patients. The adherence decreased by 2.5% per month and decreased more than three times more rapidly in drop-outs (from baseline to time of drop-out). A medical visit resulted in a temporary increase in pill intake. General linear mixed model analysis showed that the predicted outcome was worse in drop-outs than in completers and worse in recurrent episode patients than in first episode patients (the former showing a higher adherence). Adherence decreases with time during 6 months of treatment with antidepressants and is influenced by demographic and clinical variables. Completers show a higher adherence than drop-outs. The outcome was worse in recurrent episode patients than first episode patients although they had a higher adherence. | lld:pubmed |
| pubmed-article:18090506 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18090506 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18090506 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18090506 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18090506 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18090506 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:18090506 | pubmed:issn | 0268-1315 | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:AlbertAdelinA | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:DemyttenaereK... | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:DewéWalthèreW | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:MestersPatric... | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:SangeleerMich... | lld:pubmed |
| pubmed-article:18090506 | pubmed:author | pubmed-author:KatrienDe... | lld:pubmed |
| pubmed-article:18090506 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18090506 | pubmed:volume | 23 | lld:pubmed |
| pubmed-article:18090506 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18090506 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18090506 | pubmed:pagination | 36-42 | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
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| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:meshHeading | pubmed-meshheading:18090506... | lld:pubmed |
| pubmed-article:18090506 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18090506 | pubmed:articleTitle | Six-month compliance with antidepressant medication in the treatment of major depressive disorder. | lld:pubmed |
| pubmed-article:18090506 | pubmed:affiliation | University Hospital Gasthuisberg, Belgium. koen.demyttenaere@med.kuleuven.be | lld:pubmed |
| pubmed-article:18090506 | pubmed:publicationType | Journal Article | lld:pubmed |
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