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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-3
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pubmed:abstractText |
Alveolar fibrin deposition is a hallmark of pneumonia. It has been proposed that natural inhibitors of coagulation, including activated protein C, antithrombin, and tissue factor pathway inhibitor, exert lung-protective effects via anticoagulant and possibly anti-inflammatory pathways. We investigated the role of these natural anticoagulants in Streptococcus pneumoniae pneumonia.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1530-0293
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
204-10
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pubmed:meshHeading |
pubmed-meshheading:18090375-Animals,
pubmed-meshheading:18090375-Antithrombins,
pubmed-meshheading:18090375-Blood Coagulation,
pubmed-meshheading:18090375-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:18090375-Colony Count, Microbial,
pubmed-meshheading:18090375-Disease Models, Animal,
pubmed-meshheading:18090375-Male,
pubmed-meshheading:18090375-Pneumonia,
pubmed-meshheading:18090375-Pneumonia, Pneumococcal,
pubmed-meshheading:18090375-Rats,
pubmed-meshheading:18090375-Rats, Sprague-Dawley,
pubmed-meshheading:18090375-Respiratory Distress Syndrome, Adult
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pubmed:year |
2008
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pubmed:articleTitle |
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
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pubmed:affiliation |
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. godachoi@mail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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