Linked Life Data

18089911

Source:http://linkedlifedata.com/resource/pubmed/id/18089911

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-12-19
pubmed:abstractText
This follow-up study confirms our previous findings that the ER-alpha PvuII polymorphism (Pp) modulates the association between exercise and bone mass. The differences in bone properties of girls with consistently low physical activity (LLPA) and consistently high physical activity (HHPA) were evident only in those bearing the heterozygote ER-alpha genotype (Pp). In particular, areal bone mineral density of the total femur, bone mineral content and areal bone mineral density of the femoral neck, and bone mineral content and cortical thickness of the tibia shaft were significantly (p < .05) lower in the Pp girls with LLPA than in their HHPA counterparts. These findings might partly explain the genetic basis of human variation associated with exercise training.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0899-8493
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
444-58
pubmed:dateRevised
2008-2-12
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Estrogen receptor alpha polymorphism modifies the association between childhood exercise and bone mass: follow-up study.
pubmed:affiliation
Dept. Of Cell Biology, University of Jyvaskyla, Finland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't