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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-2-27
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pubmed:abstractText |
Antithrombin (AT) improves the outcome of septic patients with intravascular coagulation. However, the mechanisms underlying the therapeutic benefits of AT are not fully understood. Tumor necrosis factor-alpha (TNF-alpha) plays a critical role in the development of organ failure and intravascular coagulation in sepsis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antithrombins,
http://linkedlifedata.com/resource/pubmed/chemical/Carbazoles,
http://linkedlifedata.com/resource/pubmed/chemical/EGR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Early Growth Response Protein 1,
http://linkedlifedata.com/resource/pubmed/chemical/Epoprostenol,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP...,
http://linkedlifedata.com/resource/pubmed/chemical/Heparin,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles,
http://linkedlifedata.com/resource/pubmed/chemical/KT 5720,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/beraprost
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
499-507
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18088351-Antithrombins,
pubmed-meshheading:18088351-Carbazoles,
pubmed-meshheading:18088351-Cell Survival,
pubmed-meshheading:18088351-Early Growth Response Protein 1,
pubmed-meshheading:18088351-Epoprostenol,
pubmed-meshheading:18088351-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:18088351-Heparin,
pubmed-meshheading:18088351-Humans,
pubmed-meshheading:18088351-Indoles,
pubmed-meshheading:18088351-Lipopolysaccharides,
pubmed-meshheading:18088351-Models, Biological,
pubmed-meshheading:18088351-Monocytes,
pubmed-meshheading:18088351-Phosphorylation,
pubmed-meshheading:18088351-Platelet Aggregation Inhibitors,
pubmed-meshheading:18088351-Pyrroles,
pubmed-meshheading:18088351-Tumor Necrosis Factor-alpha
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pubmed:year |
2008
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pubmed:articleTitle |
Antithrombin inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression.
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pubmed:affiliation |
Department of Anaesthesiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
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pubmed:publicationType |
Journal Article
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