Source:http://linkedlifedata.com/resource/pubmed/id/18085465
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2007-12-18
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pubmed:abstractText |
Olopatadine 0.1% (Patanol) and olopatadine 0.2% (Pataday) ophthalmic solutions are topical ocular anti-allergic agents with antihistaminic and mast cell stabilizing properties. The efficacy of two doses of olopatadine 0.1% was compared to one dose of olopatadine 0.2% in the prevention of ocular itching associated with allergic conjunctivitis over 24 hours. This double-masked conjunctival allergen challenge (CAC) study found no significant difference in the mean itching scores between two drops of olopatadine 0.1% and one drop of olopatadine 0.2%. Both showed significant activity at the 24-hour time point and were statistically superior to placebo. No adverse events occurred while on drug therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Dibenzoxepins,
http://linkedlifedata.com/resource/pubmed/chemical/Histamine H1 Antagonists...,
http://linkedlifedata.com/resource/pubmed/chemical/Ophthalmic Solutions,
http://linkedlifedata.com/resource/pubmed/chemical/olopatadine
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0271-3683
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1017-22
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pubmed:meshHeading |
pubmed-meshheading:18085465-Adult,
pubmed-meshheading:18085465-Allergens,
pubmed-meshheading:18085465-Conjunctiva,
pubmed-meshheading:18085465-Conjunctivitis, Allergic,
pubmed-meshheading:18085465-Dibenzoxepins,
pubmed-meshheading:18085465-Double-Blind Method,
pubmed-meshheading:18085465-Female,
pubmed-meshheading:18085465-Histamine H1 Antagonists, Non-Sedating,
pubmed-meshheading:18085465-Humans,
pubmed-meshheading:18085465-Male,
pubmed-meshheading:18085465-Ophthalmic Solutions,
pubmed-meshheading:18085465-Pruritus,
pubmed-meshheading:18085465-Skin Tests,
pubmed-meshheading:18085465-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
Efficacy of once-daily olopatadine 0.2% ophthalmic solution compared to twice-daily olopatadine 0.1% ophthalmic solution for the treatment of ocular itching induced by conjunctival allergen challenge.
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pubmed:affiliation |
Harvard Medical School, Schepens Eye Research Institute, Department of Ophthalmology, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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