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pubmed-article:18085230pubmed:dateCreated2007-12-18lld:pubmed
pubmed-article:18085230pubmed:abstractTextMicrotubule-actin interactions are fundamental to many cellular processes such as cytokinesis and cellular locomotion. Investigating the mechanism of microtubule-actin interactions is the key to understand the cellular morphogenesis and related pathological processes. The abundance and highly dynamic nature of microtubules and F-actin raise a serious challenge when trying to distinguish between the real and fortuitous interactions within a cell. Xenopus oocyte wound model represents an ideal system to study microtubule-actin interactions as well as microtubule-dependent control of the actin polymerization. Here, we describe a series of cytoskeleton specific treatments in Xenopus oocyte wound healing experiments and use confocal fluorescence microscopy to analyze fixed oocytes to examine microtubule-actin interactions.lld:pubmed
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pubmed-article:18085230pubmed:statusMEDLINElld:pubmed
pubmed-article:18085230pubmed:issn1543-1894lld:pubmed
pubmed-article:18085230pubmed:authorpubmed-author:ZhangTongTlld:pubmed
pubmed-article:18085230pubmed:authorpubmed-author:MandatoCraig...lld:pubmed
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pubmed-article:18085230pubmed:volume137lld:pubmed
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pubmed-article:18085230pubmed:pagination181-8lld:pubmed
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pubmed-article:18085230pubmed:year2007lld:pubmed
pubmed-article:18085230pubmed:articleTitleXenopus oocyte wound healing as a model system for analysis of microtubule-actin interactions.lld:pubmed
pubmed-article:18085230pubmed:affiliationMcGill University, Montreal, Canada.lld:pubmed
pubmed-article:18085230pubmed:publicationTypeJournal Articlelld:pubmed