Source:http://linkedlifedata.com/resource/pubmed/id/18085230
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2007-12-18
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pubmed:abstractText |
Microtubule-actin interactions are fundamental to many cellular processes such as cytokinesis and cellular locomotion. Investigating the mechanism of microtubule-actin interactions is the key to understand the cellular morphogenesis and related pathological processes. The abundance and highly dynamic nature of microtubules and F-actin raise a serious challenge when trying to distinguish between the real and fortuitous interactions within a cell. Xenopus oocyte wound model represents an ideal system to study microtubule-actin interactions as well as microtubule-dependent control of the actin polymerization. Here, we describe a series of cytoskeleton specific treatments in Xenopus oocyte wound healing experiments and use confocal fluorescence microscopy to analyze fixed oocytes to examine microtubule-actin interactions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1543-1894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
181-8
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pubmed:meshHeading |
pubmed-meshheading:18085230-Actins,
pubmed-meshheading:18085230-Animals,
pubmed-meshheading:18085230-Female,
pubmed-meshheading:18085230-Microscopy, Confocal,
pubmed-meshheading:18085230-Microscopy, Fluorescence,
pubmed-meshheading:18085230-Microtubules,
pubmed-meshheading:18085230-Oocytes,
pubmed-meshheading:18085230-Paclitaxel,
pubmed-meshheading:18085230-Wound Healing,
pubmed-meshheading:18085230-Xenopus laevis
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pubmed:year |
2007
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pubmed:articleTitle |
Xenopus oocyte wound healing as a model system for analysis of microtubule-actin interactions.
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pubmed:affiliation |
McGill University, Montreal, Canada.
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pubmed:publicationType |
Journal Article
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