Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-1-18
pubmed:abstractText
Hookworms infect nearly a billion people. The Ancylostoma caninum hookworm of canids is a model for studying human infections and information from its genome coupled with functional genomics and proteomics can accelerate progress towards hookworm control. As a step towards a full-scale A. caninum genome project, we generated 104,000 genome survey sequences (GSSs) and determined the genome size of the canine hookworm. GSSs assembled into 57.6 Mb of unique sequence from a genome that we estimate by flow cytometry of isolated nuclei to be 347 +/- 1.2 Mb, substantially larger than other Rhabditina species. Gene finding identified 5538 genes in the GSS assembly, for a total of 9113 non-redundant A. caninum genes when EST sequences are also considered. Functional classifications of many of the 70% of genes with homology to genes in other species are provided based on gene ontology and KEGG associations and secreted and membrane-bound proteins are also identified.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-10340481, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-10592173, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-10802651, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-11125043, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-11590104, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-12176921, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-12520045, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-12646499, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-12706802, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-12952883, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-14642761, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-14681448, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-14717968, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-15111065, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-15571632, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-15574829, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-15854223, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-15898832, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16056220, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16093699, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16187796, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16381856, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16445914, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-16905262, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-17202162, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-17989781, http://linkedlifedata.com/resource/pubmed/commentcorrection/18082904-8636085
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0166-6851
pubmed:author
pubmed:issnType
Print
pubmed:volume
157
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-92
pubmed:dateRevised
2011-5-5
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
The canine hookworm genome: analysis and classification of Ancylostoma caninum survey sequences.
pubmed:affiliation
Department of Genetics, Genome Sequencing Center, Washington University School of Medicine, St Louis, MO 63108, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural