Source:http://linkedlifedata.com/resource/pubmed/id/18081723
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-3-7
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pubmed:abstractText |
Cholelithiasis has been observed with high incidence in beta-thalassemia/hemoglobin E (beta-thal/Hb E). Recent studies have shown that a variant TATA-box in the promoter region of the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene is associated with the development of cholelithiasis. The coding region mutation (G71R) of the UGT1A1 gene was higher in Asians than those in Caucasians. The relationship between the variant UGT1A1 promoter and coding region gene and cholelithiasis in beta-thal/Hb E subjects were investigated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1600-0609
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
351-5
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18081723-Adult,
pubmed-meshheading:18081723-Alleles,
pubmed-meshheading:18081723-Cholelithiasis,
pubmed-meshheading:18081723-Female,
pubmed-meshheading:18081723-Genotype,
pubmed-meshheading:18081723-Glucuronosyltransferase,
pubmed-meshheading:18081723-Hemoglobin E,
pubmed-meshheading:18081723-Humans,
pubmed-meshheading:18081723-Male,
pubmed-meshheading:18081723-Middle Aged,
pubmed-meshheading:18081723-Mutation,
pubmed-meshheading:18081723-Open Reading Frames,
pubmed-meshheading:18081723-Polymorphism, Genetic,
pubmed-meshheading:18081723-Promoter Regions, Genetic,
pubmed-meshheading:18081723-beta-Thalassemia
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pubmed:year |
2008
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pubmed:articleTitle |
Association between promoter and coding region mutations of UDP-glucuronosyltransferase 1A1 and beta-thalassemia/Hb E with cholelithiasis.
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pubmed:affiliation |
Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok, Thailand. jranut@pmk.ac.th
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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