Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-12-13
pubmed:abstractText
Cancer is one of the most frequent causes of death in Germany. The reasons of various cancer diseases still remain uncertain. There is a long-standing discussion about associations between personality, depression, stress, and stressful life events, respectively, and the development of malignant neoplasms. Evidence for a role of psychosocial factors in development of cancer is not unequivocal despite many years of research on the subject. Current prospective investigations do not support the conventional wisdom of a direct influence for personality in the development of cancer. Much of the research has been impaired by methodological flaws such as inadequate sample size, failure to adjust for potential confounders, lengths of follow-up, use of a variation of different measurements of cancer, and psychosocial variables. Furthermore, specific personality traits and various life events are associated with certain health-related behavior and lifestyle factors, e.g., smoking or an unhealthy nutrition. These unhealthy habits can increase cancer risk. Psychological parameters may alter immune and endocrine function and it has long been hypothesized that, through this pathway, psychosocial factors may affect cancer incidence. In conclusion, study results to substantiate the role of psychosocial factors in the development of various cancers are inconclusive. Contradictory results may be explained by methodological shortcomings. Further studies are required to pursue this question further.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0723-5003
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
102
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
967-79
pubmed:dateRevised
2009-11-3
pubmed:meshHeading
pubmed-meshheading:18075717-Adult, pubmed-meshheading:18075717-Aged, pubmed-meshheading:18075717-Aged, 80 and over, pubmed-meshheading:18075717-Case-Control Studies, pubmed-meshheading:18075717-Cohort Studies, pubmed-meshheading:18075717-Data Interpretation, Statistical, pubmed-meshheading:18075717-Depression, pubmed-meshheading:18075717-Female, pubmed-meshheading:18075717-Follow-Up Studies, pubmed-meshheading:18075717-Health Behavior, pubmed-meshheading:18075717-Humans, pubmed-meshheading:18075717-Life Change Events, pubmed-meshheading:18075717-Life Style, pubmed-meshheading:18075717-Lung Neoplasms, pubmed-meshheading:18075717-Male, pubmed-meshheading:18075717-Middle Aged, pubmed-meshheading:18075717-Neoplasms, pubmed-meshheading:18075717-Personality, pubmed-meshheading:18075717-Prospective Studies, pubmed-meshheading:18075717-Psychology, pubmed-meshheading:18075717-Risk Factors, pubmed-meshheading:18075717-Smoking, pubmed-meshheading:18075717-Time Factors
pubmed:year
2007
pubmed:articleTitle
[Psychosocial risk factors for cancer development].
pubmed:affiliation
Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Klinishches Forschungszentrum Frauengesundheit, Berlin.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Review