rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-12-12
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pubmed:abstractText |
Loss-of-function mutations in the filaggrin gene (FLG) have been strongly associated with atopic dermatitis and allergic phenotypes in multiple populations. The role of these mutations in the development of asthma is less clear, particularly in patients who do not have coincident atopic dermatitis.
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pubmed:grant |
|
pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
1097-6825
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1332-7
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pubmed:dateRevised |
2008-7-1
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pubmed:meshHeading |
pubmed-meshheading:18073125-Asthma,
pubmed-meshheading:18073125-Case-Control Studies,
pubmed-meshheading:18073125-Child,
pubmed-meshheading:18073125-Child, Preschool,
pubmed-meshheading:18073125-Codon, Nonsense,
pubmed-meshheading:18073125-Dermatitis, Atopic,
pubmed-meshheading:18073125-Female,
pubmed-meshheading:18073125-Frameshift Mutation,
pubmed-meshheading:18073125-Genetic Predisposition to Disease,
pubmed-meshheading:18073125-Humans,
pubmed-meshheading:18073125-Intermediate Filament Proteins,
pubmed-meshheading:18073125-Male,
pubmed-meshheading:18073125-Phenotype,
pubmed-meshheading:18073125-Sequence Deletion,
pubmed-meshheading:18073125-Severity of Illness Index
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pubmed:year |
2007
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pubmed:articleTitle |
Filaggrin mutations confer susceptibility to atopic dermatitis but not to asthma.
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pubmed:affiliation |
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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