Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1992-5-19
|
| pubmed:abstractText |
A series of omega-dialkylaminoalkyl esters of 3-dialkylamino-4,7,7-trimethyl-N-phenylbicyclo[2.2.1]hept-2-ene-2- iminothiolic acids 3 was prepared by reaction of 4,7,7-trimethyl-3-(dimethylamino or 1-piperidinyl)-N-phenylbicyclo[2.2.1] hept-2-ene-2-thiocarboxamides with a number of omega-chloroalkyldialkylamines in the presence of sodium hydride in DMF or benzene solution. Some esters 3 showed an appreciable local anesthetic activity in mice.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0014-827X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
46
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1033-41
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1807289-Anesthetics, Local,
pubmed-meshheading:1807289-Animals,
pubmed-meshheading:1807289-Anti-Arrhythmia Agents,
pubmed-meshheading:1807289-Bicyclo Compounds,
pubmed-meshheading:1807289-Blood Pressure,
pubmed-meshheading:1807289-Magnetic Resonance Spectroscopy,
pubmed-meshheading:1807289-Mice,
pubmed-meshheading:1807289-Pain Measurement,
pubmed-meshheading:1807289-Rats,
pubmed-meshheading:1807289-Spectrophotometry, Infrared,
pubmed-meshheading:1807289-Thiocyanates
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
omega-Dialkylaminoalkyl esters of 3-dialkylamino-4,7,7-trimethyl-N-phenylbicyclo[2.2.1] hept-2-ene-2-iminothiolic acids with local anesthetic activity.
|
| pubmed:affiliation |
Istituto di Scienze Farmaceutiche dell'Università, Genova, Italy.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|