rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2008-4-8
|
pubmed:abstractText |
The DG10S478 variant in the transcription factor 7-like 2 (TCF7L2) gene is a tetranucleotide repeat with six alleles. Alleles 0, 8 and 12 were found to account for 98% of chromosomes in population based controls. The composite allele X (non zero) has been associated with type 2 diabetes while allele 0 (no insertion) was described as protective. However, no data exist about the influence of DG10S478 variants on manifestation of diabetes and development of diabetic complications.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0947-7349
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
116
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
211-4
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:18072015-Aged,
pubmed-meshheading:18072015-Diabetes Mellitus, Type 2,
pubmed-meshheading:18072015-Diabetic Angiopathies,
pubmed-meshheading:18072015-Diabetic Nephropathies,
pubmed-meshheading:18072015-Diabetic Retinopathy,
pubmed-meshheading:18072015-Female,
pubmed-meshheading:18072015-Genetic Variation,
pubmed-meshheading:18072015-Heterozygote Detection,
pubmed-meshheading:18072015-Homozygote,
pubmed-meshheading:18072015-Humans,
pubmed-meshheading:18072015-Male,
pubmed-meshheading:18072015-Middle Aged,
pubmed-meshheading:18072015-Outpatients,
pubmed-meshheading:18072015-TCF Transcription Factors,
pubmed-meshheading:18072015-Transcription Factor 7-Like 2 Protein
|
pubmed:year |
2008
|
pubmed:articleTitle |
The DG10S478 variant in the TCF7L2 gene is not associated with microvascular complications in type 2 diabetes.
|
pubmed:affiliation |
Department of Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany. Susanne.Buchbinder@med.uni-heidelberg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|