Linked Life Data

18070965

Source:http://linkedlifedata.com/resource/pubmed/id/18070965

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-2-26
pubmed:abstractText
Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp. are resistant to five antimicrotubule compounds, unlike any other eukaryote studied so far. Resistance correlates with critical amino acid differences within the inhibitor binding sites of the tubulin heterodimers.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-10029309, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-10427726, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-10546848, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-10602676, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-11286798, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-11700061, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-12370037, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-12692099, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-14070392, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-14742718, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-15184082, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-15500920, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-15695656, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-15917812, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-1686112, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-1740534, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-423966, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-6378710, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-7811023, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-7911975, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-8663038, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-8948325, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-9034567, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-9428769, http://linkedlifedata.com/resource/pubmed/commentcorrection/18070965-9687403
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0066-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1133-5
pubmed:dateRevised
2010-9-22
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds.
pubmed:affiliation
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, United Kingdom. fiona.henriquez@paisley.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't