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pubmed-article:18070210pubmed:abstractTextPemphigus is a life-threatening autoimmune blistering disease usually treated with high-dose corticosteroids and other immunosuppressants. However, this regimen may prove inadequate in severe cases and cause dangerous side-effects. While protein A immunoadsorption (PAIA) induces a rapid remission in severe pemphigus, the disease usually recurs once the treatment is stopped. In contrast, anti-CD20 antibody rituximab has a delayed onset of action but may lead to a long-term remission of pemphigus.lld:pubmed
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pubmed-article:18070210pubmed:articleTitleTreatment of severe pemphigus with protein A immunoadsorption, rituximab and intravenous immunoglobulins.lld:pubmed
pubmed-article:18070210pubmed:affiliationDepartment of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. shim92@hotmail.comlld:pubmed
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