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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-24
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pubmed:abstractText |
Pemphigus is a life-threatening autoimmune blistering disease usually treated with high-dose corticosteroids and other immunosuppressants. However, this regimen may prove inadequate in severe cases and cause dangerous side-effects. While protein A immunoadsorption (PAIA) induces a rapid remission in severe pemphigus, the disease usually recurs once the treatment is stopped. In contrast, anti-CD20 antibody rituximab has a delayed onset of action but may lead to a long-term remission of pemphigus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-0963
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
382-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18070210-Adult,
pubmed-meshheading:18070210-Aged,
pubmed-meshheading:18070210-Antibodies, Monoclonal,
pubmed-meshheading:18070210-Antibodies, Monoclonal, Murine-Derived,
pubmed-meshheading:18070210-Combined Modality Therapy,
pubmed-meshheading:18070210-Drug Therapy, Combination,
pubmed-meshheading:18070210-Female,
pubmed-meshheading:18070210-Humans,
pubmed-meshheading:18070210-Immunoglobulins, Intravenous,
pubmed-meshheading:18070210-Immunologic Factors,
pubmed-meshheading:18070210-Immunosorbent Techniques,
pubmed-meshheading:18070210-Male,
pubmed-meshheading:18070210-Middle Aged,
pubmed-meshheading:18070210-Pemphigus,
pubmed-meshheading:18070210-Staphylococcal Protein A,
pubmed-meshheading:18070210-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Treatment of severe pemphigus with protein A immunoadsorption, rituximab and intravenous immunoglobulins.
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pubmed:affiliation |
Department of Dermatology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. shim92@hotmail.com
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pubmed:publicationType |
Journal Article
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