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pubmed:abstractText |
Molecular target therapy is the most progressive and promising anticancer therapy in last decade. Multiple myeloma is also one of the major therapeutic targets for using molecular based technology. The recent availability of clinical data regarding thalidomide-, lenalidomide-, and bortezomib-based regimens has provided new, effective treatment options for patients with both newly diagnosed and relapsed/refractory multiple myeloma. We are expecting that future clinical trials can be designed to achieve a high likelihood of success based on molecular studies, cell-signaling, and correlative science studies. Studies with these agents also provide new insight into the cancer biology underlying multiple myeloma in humans.
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